减少胎儿运动和COVID-19感染:一个回顾性队列研究
Amira Gentili1, Irene Sterpu2, Joanna Tingström1
1Department of Clinical Science and Education, Department of Obstetrics and Gynecology, Karolinska Institute, Sodersjukhuset, Stockholm, 118 83, Sweden.
BMC pregnancy and childbirth
|January 30, 2025
概括
减少胎儿运动 (RFM) 在COVID-19大流行期间没有增加不良结果. 然而,与多个孩子的母亲相比,患有RFM的初次母亲面临的胎儿不良后果风险增加了两倍.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 传染性疾病 传染性疾病
背景情况:
- 减少胎儿运动 (RFM) 是胎儿福祉的关键指标,可能是胎儿生长限制 (FGR) 或子宫内胎儿死亡 (IUFD) 的信号.
- 随着COVID-19大流行,人们担心胎儿不良结果的增加,包括早产和IUFD.
- COVID-19对RFM怀孕的影响尚不清楚.
研究的目的:
- 评估2020年与2019年相比,RFM患者的女性中胎儿不良结果是否增加.
- 确定怀孕期间母亲的COVID-19感染是否是RFM妇女不良结果的危险因素.
主要方法:
- 一项回顾性研究包括在2019年至2020年期间在索德医院分娩后呈现RFM的妇女.
- 对胎儿综合结果进行了分析,并比较了COVID-19感染和没有感染的女性.
主要成果:
- 在接受RFM的女性中,COVID-19感染并没有增加胎儿不良结果的风险.
- 与多发性妇女相比,患有RFM的初发性妇女的胎儿不良结果风险是多发性妇女的两倍 (AOR=2.5).
- 在COVID-19阳性组中,复合结果略高一些,但这种差异在统计学上并不显著.
结论:
- 在患有RFM的女性中,不良综合结果的发生率在COVID-19大流行的最初一年没有增加.
- 没有发现母体COVID-19感染是RFM妇女不良胎儿结果的重要风险因素.
- 在女性呈现RFM时,Primiparity成为不良胎儿结果的重要风险因素.
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