怀孕期间的受孕季节和高血压疾病的风险
Yanxia Xie1, Yi Mu1, Peiran Chen1
1National Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, No. 17, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
BMC pregnancy and childbirth
|January 30, 2025
概括
春季怀孕使怀孕期间高血压障碍 (HDP) 的风险增加10%. 这项研究强调了季节性变化和环境因素可能导致HDP病因.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇健康 孕产妇健康
- 流行病学 流行病学
背景情况:
- 怀孕期间高血压障碍 (HDP) 是一种常见的产科疾病,主要原因不明.
- 调查怀孕的季节性变化可能会揭示HDP的环境风险因素.
研究的目的:
- 探索怀孕季节与怀孕期间患高血压疾病的风险之间的关联.
- 识别潜在的季节性模式和环境对HDP发展的影响.
主要方法:
- 利用了2012-2021年中国国家孕产妇近亲监测系统 (NMNMSS) 的数据.
- 估计怀孕日期并将它们分为四个季节:冬季,春季,夏季和秋季.
- 运用后勤回归来计算基于受孕季节的HDP风险赔率比率.
主要成果:
- 春季怀孕与夏季怀孕相比,HDP的风险增加了10% (aOR,1.10).
- 在2月,3月,4月,5月和6月的怀孕中,发现了增加的HDP风险.
- 关联在气候区之间有所不同,对于妊娠高血压和子宫前更为强烈.
结论:
- 在HDP风险存在显著的季节性变化,受母亲特征,HDP亚型和气候区域的影响.
- 季节性波动的环境因素在HDP的病因研究中需要考虑.
相关概念视频
01:07Teratogenicity
2.3K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.3K
01:33Hormonal Regulation
32.8K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
32.8K
01:18Hypertension and Regulation of Blood Pressure
1.9K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
1.9K
01:22Diabetes Mellitus: Type 2 and Gestational
2.1K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.1K
01:17Measurement of Blood Pressure
827
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
827
01:14Fetal Circulation
768
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
768