试索病对雄性驼不孕症的影响
Sara Salah Abdel-Hakeem1, Gaber Megahed2, Ahmed M Al-Hakami3
1Parasitology Laboratory, Department of Zoology and Entomology, Faculty of Science, Assiut University, Asyut, Egypt.
Frontiers in veterinary science
|January 31, 2025
概括
阿拉伯驼中Trypanosoma evansi感染显著影响男性生育能力,导致丸损伤和荷尔蒙失衡. 通过生理和荷尔蒙标记的早期检测对于管理牲畜中这种血液寄生虫至关重要.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 驼繁殖的繁殖方式
- 分子生物学分子生物学
背景情况:
- 血液寄生虫,特别是Trypanosoma evansi,对畜牧业构成重大威胁,特别影响驼.
- 驼不孕症是一个越来越令人担忧的问题,可能与传染性疾病 (如三虫病) 有关.
研究的目的:
- 为了确定阿拉伯驼中Trypanosoma evansi的流行率.
- 调查T. evansi感染对雄性驼生殖健康的影响,包括血清蛋白,脂质,生殖指数和热冲击蛋白70 (HSP70) 表达.
主要方法:
- 检测T. evansi的显微镜和血清学检查.
- 对血清蛋白质分数和脂质概况的分析.
- 在感染和健康的驼中评估丸组织病理学,水平和HSP70表达.
主要成果:
- 在研究的驼群体中,发现T. evansi感染的患病率为23.4%.
- 受感染的驼显示出总血清蛋白增加,丸退行,丸激素减少和HSP70表达升高.
- 蛋白质组分析揭示了受感染的驼中不同的蛋白质分数.
结论:
- 感染Trypanosoma evansi会通过丸损伤和荷尔蒙干扰显著损害雄性驼的生育能力.
- 包括HSP70表达在内的生理和荷尔蒙分析可以作为诊断驼T. evansi感染的可靠指标.
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