装载着Lactobacillus rhamnosus生物活性代谢物的奇托桑纳米颗粒:制备,表征和抗真菌活性
Aya Abdel-Nasser1, Hayam M Fathy2, Ahmed N Badr1
1Food Toxicology and Contaminants Department, National Research Centre, Egypt.
Heliyon
|January 31, 2025
概括
装有Lactobacillus rhamnosus代谢物的奇托桑纳米颗粒有效地对抗玉米中的Aspergillus flavus,减少了超过89%的真菌生长. 这一创新为粮食安全和粮食安全提供了一个有希望的自然解决方案.
科学领域:
- 农业科学 农业科学
- 食品科学 食品科学 食品科学
- 微生物学 微生物学
背景情况:
- 阿斯伯吉勒斯黄菌 (Aspergillus flavus) 由于受到亚毒素污染,对全球玉米 (Zea mays) 种植构成重大威胁.
- 非洲毒素对人类和动物的健康构成风险,并造成重大经济损失.
- 基于天然成分的涂层是控制A. flavus.的一个有希望的策略.
研究的目的:
- 为了研究Lactobacillus rhamnosus生物活性代谢物纳入奇托桑纳米颗粒的抗真菌功效,针对阿斯伯吉卢斯黄菌.
- 描述开发的充满L. rhamnosus生物活性代谢物的奇多纳米颗粒的物理化学性质.
主要方法:
- 装有L. rhamnosus生物活性代谢物的基托桑纳米颗粒使用TEM,zeta潜力,尺寸分布,PDI,pH,封装效率和FTIR进行了合成和表征.
- 对玉米核上的A. flavus进行了抗真菌活性评估.
- 评估了发芽抑制和生存率.
主要成果:
- 传输电子显微镜证实了球形奇托桑纳米颗粒,直径增加与更高的代谢物度相关.
- 泽塔潜力和尺寸分布随着L. rhamnosus代谢物负载的增加而增加.
- 含有7毫克/毫升L. rhamnosus生物活性代谢物的奇托桑纳米颗粒在10天后将玉米上的A. flavus生长率降低了89.42%,也降低了发芽抑制和活力.
结论:
- 整合到奇托纳米颗粒中的Lactobacillus rhamnosus生物活性代谢物显示出对Aspergillus flavus的强有力的抗真菌活性.
- 这种配方显示出通过减轻谷物中的真菌污染来提高食品安全的巨大潜力.
- 该研究强调了一种可行的自然方法来保护玉米种植和确保谷物质量.
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