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Updated: May 16, 2026

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall
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开发人类上,下和深肺气道模型:结合不同的支架和开发复杂的共同文化.

Rasika S Murkar1, Cornelia Wiese-Rischke2, Tobias Weigel3

  • 1Core Facility Tissue Engineering, Institute of Chemistry, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.

Journal of tissue engineering
|January 31, 2025
PubMed
概括

开发先进的3D气道模型需要仔细选择脚手架. 细胞共同培养显著影响气道组织模型的功能,远远超过单独的支架材料.

关键词:
三维微环境是3D微环境.空气道组织模型细胞系 (Calu-3和A549) 的细胞系.共同文化是一种共同文化.原和合成脚手架生物材料深肺气泡 (深肺气泡) 是一个深肺气泡.电力旋转是指电力旋转.细胞外矩阵 (ECM) 是一个细胞外矩阵.下呼吸道的下部呼吸道.人类初级细胞和干细胞.上空气道上空气道上空气道

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Anatomy of Respiratory System I: Upper Respiratory Tract

The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
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Anatomy of Respiratory System II: Lower Respiratory Tract

The lower respiratory tract is anatomically composed of several vital structures, including the larynx, trachea, bronchial tree, alveoli, lungs, and pleurae. Each component has a specific function, and all are intricately connected to ensure efficient respiration.
The Larynx
It is located between the pharynx and the trachea, acts as a passageway for air, and hosts several critical structures, such as the epiglottis, vocal cords, and glottis. The epiglottis acts as a gateway, guiding food to the...
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Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...