与轴性脊柱炎相关的亚大西洋轴突突:基于病例的系统性审查
Maroua Slouma1,2, Soumaya Rezgui1,2, Houssem Tbini1,2
1Department of Rheumatology.
Mediterranean journal of rheumatology
|January 31, 2025
概括
大西洋轴位是轴性脊柱炎的一个罕见并发症. 早期识别和手术治疗对于预防严重的神经缺陷和受影响患者的潜在死亡率至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 整形外科 整形外科 整形外科
- 神经外科 神经外科
背景情况:
- 大西洋轴突 (Atlantoaxial dislocation,简称AAD) 是一个罕见的,大西洋 (C1) 和轴 (C2) 脊椎之间的不稳定性.
- 在被诊断为轴性脊柱炎 (AxSpA) 的患者中很少报告.
- 本案例报告突出了AXSpA被AAD揭露的一个例子.
研究的目的:
- 介绍一个AxSpA病例,最初通过急性大西洋轴突突变被诊断出来.
- 在AxSpA的背景下审查AAD的文献.
- 了解AxSpA患者AAD的临床表现,治疗和结果.
主要方法:
- 通过使用MEDLINE进行文献综述,并遵守PRISMA指南.
- 包括以AXSpA患者的AAD为重点的病例报告和病例系列.
- 数据提取包括患者人口统计,临床表现,AAD类型和治疗结果.
主要成果:
- 该审查包括16篇文章,共计134名患者 (119名男性,平均年龄为34.43岁).
- AAD在4例病例中发现了AxSpA;常见症状包括部疼痛,四肢虚弱/麻木,以及宫运动受限.
- 以前的AAD是最常见的 (118例); 手术治疗 (C1-C2关节骨折) 是首选的,在大多数详细的病例中具有有利的结果.
结论:
- 医生必须在AxSpA患者中保持对AAD的高度怀疑指数.
- AAD可以导致严重的并发症,如脊髓和血管压缩,需要手术干预.
- 及时诊断和管理对于改善患者的治疗结果和预防危及生命的事件至关重要.
相关概念视频
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