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Updated: May 30, 2025

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
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在trans-Acyltransferase Polyketide Synthases中通过乙烯基水解酶进行短链酸水解的分子基础

Christopher D Fage1,2, Munro Passmore1, Ben P Tatman1,3

  • 1Department of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.

JACS Au
|January 31, 2025
PubMed
概括

这项研究揭示了乙化酶 (AHs) 如何通过在跨乙转移酶聚乙合成酶 (PKSs) 中选择性地从乙载体蛋白 (ACPs) 中去除乙基来控制聚乙链长度. 这说明了天然产品生物合成的一个关键步骤.

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