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Updated: May 30, 2025

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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原生质谱法捕捉了具有低复杂性域的蛋白质的形态可塑性

Hannah Osterholz1, Alexander Stevens1, Mia L Abramsson2

  • 1Department of Cell and Molecular Biology, Uppsala University, 751 24 Uppsala, Sweden.

JACS Au
|January 31, 2025
PubMed
概括

原生质谱 (nMS) 现在可以分析具有无序低复杂性 (LC) 域的蛋白质,揭示它们的结构可塑性和相互作用的洞察力,这对于理解细胞凝聚物至关重要.

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