[人类是否与肠道微生物群共同进化?]
1Département de microbiologie fondamentale, université de Lausanne, Lausanne, Suisse.
概括
肠道微生物组在个体内迅速发展,适应饮食并影响健康. 然而,长期的人类进化与大多数肠道微生物进化脱,这是由于人与人之间的微生物交换.
科学领域:
- 微生物学 微生物学
- 进化生物学 进化生物学
- 人体生理学 人体生理学
背景情况:
- 肠道微生物组对于动物生理学和发育至关重要.
- 了解肠道微生物组的进化历史是有限的.
- 关于微生物组的进化,起源和与人类共同进化的关键问题仍然存在.
研究的目的:
- 探索肠道微生物组的进化历史.
- 研究肠道微生物进化的速度 (微观进化与宏观进化).
- 检查肠道微生物组进化和人类适应之间的关系.
主要方法:
- 这项研究是对当前关于肠道微生物组演变的知识的审查和综合.
- 它分析了短期 (微观进化) 和长期 (宏观进化) 的进化过程.
- 它考虑了宿主种群之间的微生物交换.
主要成果:
- 肠道微生物表现出快速的微观进化,适应环境变化,如个体内的饮食.
- 人类的长期进化在很大程度上与大多数肠道微生物的进化脱,这是由于人类之间的微生物转移.
- 大多数肠道微生物在几千年的时间里,在宿主群体之间有着交换的历史.
结论:
- 肠道微生物在个体内迅速发展,影响健康.
- 虽然肠道微生物的进化速度很快,但它们的长期进化轨迹与人类进化不同.
- 微生物组进化在促进人类在几十万年的适应过程中的作用是一个开放的研究问题.
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