[过早衰老的系统机制及其通过复杂的物理治疗应用的纠正]
N B Korchazhkina1, A A Mikhailova1, K V Kotenko1
1Federal State Budgetary Scientific Institution «Russian Scientific Center of Surgery named after Academician B.V. Petrovsky», Moscow, Russia.
Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury
|January 31, 2025
概括
多模式物理治疗有效地通过改善新陈代谢和减少生物年龄来对抗衰老. 标准的预防方法是不够的,突出需要先进的干预措施,以促进健康的长寿.
科学领域:
- 老年学和衰老研究研究.
- 预防医学和健康span延长
- 物理治疗和康复疗法
背景情况:
- 人类的衰老与加速生物衰老并缩短活跃寿命的疾病有关.
- 识别病理反应的预测因素对于开发有效的抗衰老策略至关重要.
- 需要对与年龄相关的功能变化进行系统分析,以了解和缓解衰老过程.
研究的目的:
- 在本体发生过程中对功能系统的病理变化进行系统分析.
- 评估多模式物理治疗在老年患者的健康保护方面的有效性.
- 探索预防策略,以提高活跃寿命.
主要方法:
- 一项涉及俄罗斯国家癌症中心80名年龄在20-90岁的患者的研究.
- 患者被随机分为一个比较组 (标准护理) 和一个主要组 (标准护理+多模式物理治疗).
- 多模式物理治疗包括阿尔法LED光疗,超低氧治疗,压力治疗和干燥的二氧化碳浴,在6个月内重复两次.
主要成果:
- 由于代谢障碍,炎症和缩短的端粒,衰老加速生物年龄,比以前想象的更早开始.
- 标准预防措施 (活动,饮食,维生素) 在对照组中没有显示任何益处,而脂肪代谢恶化.
- 复杂的物理治疗显著降低了生物年龄,优化了新陈代谢,并减少了炎症标志物.
结论:
- 代谢障碍,特别是胰岛素抵抗,是增加生物年龄和加速衰老的关键驱动因素.
- 标准的预防性建议对于对抗病态衰老是不够的.
- 多模式物理治疗提供了一种无副作用的方法来激活健康基因反应并促进健康的长寿.
相关概念视频
Aging
36
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
36
The Effect of Aging on Tissues
2.0K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.0K
Mitochondria
9.9K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
9.9K
Pathophysiology of Heart Failure
1.5K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.5K
Electron Transport Chain: Complex I and II
10.6K
The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...
ROS generation is regulated and maintained at moderate levels necessary...
10.6K
Stem Cell Therapy for Tissue Regeneration
4.0K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.0K


