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在Mycobacterium tuberculosis中通过结构同质性识别cAMP受体蛋白中的Allosteric热点

Stephen P Dokas1, Daniel K Taylor1, Lydia L Good1

  • 1Department of Chemistry, Georgetown University, Washington, District of Columbia 20057, United States.

Biochemistry
|January 31, 2025
PubMed
概括

循环腺单酸盐 (cAMP) 不同调节细菌cAMP受体蛋白 (CRP). 影响Mycobacterium tuberculosis CRP中cAMP结合的突变会影响其DNA相互作用和寡合化,与大肠杆菌CRP不同.

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