Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Autoimmune Disorders01:29

Autoimmune Disorders

379
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
379
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

437
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
437
Dementia01:30

Dementia

92
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
92
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

158
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
158
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

1.1K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.1K
What is the Immune System?01:38

What is the Immune System?

110.1K
Overview
110.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Botulinum toxin treatment for multiple sclerosis and post-stroke spasticity in clinical practice: differences in injection doses and patterns.

Frontiers in rehabilitation sciences·2026
Same author

Immuno-Proteomic Features Associated to Relapse Risk in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.

Neurology(R) neuroimmunology & neuroinflammation·2026
Same author

Immunity Gone Viral: Subacute Cognitive Decline With Multifocal Brain Lesions in Neuromyelitis Optica Spectrum Disorder.

Neurology(R) neuroimmunology & neuroinflammation·2026
Same author

IL-6 Receptor Blockade as Rescue Therapy in Acute Attacks of MOGAD and AQP4+NMOSD.

JAMA neurology·2026
Same author

Acute management of adult MOG antibody-associated disease: therapeutic choices and clinical outcomes.

Expert opinion on emerging drugs·2026
Same author

Long-Term Outcomes in Stiff Person Spectrum Disorder.

European journal of neurology·2026
Same journal

Neuroimaging in older-age bipolar disorder.

Current opinion in psychiatry·2026
Same journal

Repetitive transcranial magnetic stimulation treatment for obsessive-compulsive disorder.

Current opinion in psychiatry·2026
Same journal

Pharmacological maintenance treatment in older age bipolar disorder.

Current opinion in psychiatry·2026
Same journal

Harmful behaviours and suicide in later life bipolar disorder.

Current opinion in psychiatry·2026
Same journal

Urbanization, wildfire exposure, and youth mental health: a narrative review.

Current opinion in psychiatry·2026
Same journal

Bipolar disorder and the risk of developing dementia - a systematic review and meta-analysis.

Current opinion in psychiatry·2026
查看所有相关文章

相关实验视频

Updated: May 30, 2025

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

3.4K

自免疫性痴呆症是一种自免疫性痴呆.

Alessandro Dinoto1,2, Eoin P Flanagan1,3

  • 1Department of Neurology and Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, Rochester, Minnesota, USA.

Current opinion in psychiatry
|January 31, 2025
PubMed
概括
此摘要是机器生成的。

自身免疫性痴呆是一种潜在的可治疗的神经疾病. 通过临床,放射学和实验室发现的快速识别对于有效的免疫治疗和改善患者结果至关重要.

更多相关视频

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

747
A Simple Cell-based Immunofluorescence Assay to Detect Autoantibody Against the N-Methyl-D-Aspartate NMDA Receptor in Blood
07:20

A Simple Cell-based Immunofluorescence Assay to Detect Autoantibody Against the N-Methyl-D-Aspartate NMDA Receptor in Blood

Published on: January 9, 2018

9.8K

相关实验视频

Last Updated: May 30, 2025

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

3.4K
Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

747
A Simple Cell-based Immunofluorescence Assay to Detect Autoantibody Against the N-Methyl-D-Aspartate NMDA Receptor in Blood
07:20

A Simple Cell-based Immunofluorescence Assay to Detect Autoantibody Against the N-Methyl-D-Aspartate NMDA Receptor in Blood

Published on: January 9, 2018

9.8K

科学领域:

  • 神经学 神经学
  • 免疫学 免疫学 免疫学

背景情况:

  • 自免疫神经学已经迅速发展,识别了新的抗体和疾病.
  • 自免疫源的认知衰退比以前认为的更频繁.
  • 早期诊断自身免疫性痴呆症对于及时治疗和更好的预后至关重要.

研究的目的:

  • 总结自身免疫性痴呆症的临床,放射学和实验室发现.
  • 帮助临床医生及时识别这种情况.
  • 强调准确诊断和差异诊断的重要性.

主要方法:

  • 临床特征的全面审查.
  • 放射学发现的分析.
  • 实验室检测特定的自身抗体.

主要成果:

  • 自体抗体的特异性可以预测治疗反应和癌症相关性.
  • 对发现的过度解释可能导致错误的诊断和不适当的治疗.
  • 自免疫性痴呆症的诊断需要整合临床,放射学和实验室数据.

结论:

  • 自身免疫性痴呆症是一种可治疗的疾病,有可能通过免疫疗法恢复性.
  • 准确的诊断依赖于对患者数据的整体审查,并排除其他痴呆病因.
  • 错误诊断可能导致不可逆转的认知衰退,强调需要临床警.