在墨西哥COVID-19感染后的受试者中执行功能
Adriana Aguayo Arelis1, Jesús Emmanuel Arana Yepez2, Brenda Viridiana Rabago Barajas1
1Departamento de Psicologia Aplicada, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Jalisco, Mexico.
Applied neuropsychology. Adult
|January 31, 2025
概括
轻度COVID-19幸存者表现出特定的执行功能缺陷,特别是在认知灵活性方面. 这表明潜在的前额叶皮质改变,即使在非住院的个体,保证进一步的神经生理学研究.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 传染性疾病 传染性疾病
背景情况:
- 关于COVID-19对执行功能和额叶的影响存在相互矛盾的证据.
- 了解这些影响对于患者的长期康复和神经健康至关重要.
- 以前的研究还没有完全阐明受到轻度SARS-CoV-2感染影响的特定认知领域.
研究的目的:
- 评估从轻度COVID-19中恢复过来的个体的执行功能.
- 为了确定SARS-CoV-2感染后认知功能的特定缺陷.
- 探索前额叶皮层中潜在的神经生理学变化的可能性.
主要方法:
- 评估了60名具有轻度COVID-19病史的个人队列.
- 认知功能使用Trail Making Test Form B,Stroop Color和Word Test以及修改后的威斯康星州卡片排序测试 (M-WCST) 进行了评估.
- 结果与墨西哥人口的流行前历史对照进行了比较.
主要成果:
- 在COVID-19后的组显示,仅在M-WCST上得分明显较低.
- 在其他评估的执行职能中没有观察到广泛的损害.
- 缺陷集中在测量认知灵活性的任务中,由前额叶皮层介导.
结论:
- 从轻度COVID-19中恢复过来的个人不会表现出广泛的执行功能障碍.
- 在M-WCST上的特定缺陷表明前额叶皮层的潜在神经生理变化.
- 研究结果强调,即使非住院COVID-19患者也可能出现执行功能缺陷,需要进一步研究.
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