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金属杂碳的毒理影响量子点

Jyotsna Mishra¹, Tejas Suryawanshi¹, Neha Redkar²

¹Center for Research in Nano Technology and Science (CRNTS), Indian Institute of Technology, Bombay, Mumbai, 400076, India.

|January 31, 2025

概括

合金属的碳量子点 (CQD) 显示出不同的环境毒性. 用银添加的CQD (Ag-CQD) 对细菌,哺乳动物细胞和植物具有高度毒性,而用添加的CQD (Mn-CQD) 则具有较低的毒性.

科学领域:

环境科学环境科学
材料科学材料科学材料科学
毒理学毒理学毒理学

背景情况:

碳量子点 (CQD) 被探索为传统量子点和染料的更安全替代品.
金属兴奋剂增强了CQD的特性,但可能会重新引入毒性和环境风险.
生态毒理学研究对于了解金属化CQDs对环境的影响至关重要.

研究的目的:

合成和评估金属合CQDs (Mn,Fe,Cu,Ag) 的生态毒性.
评估这些CQD对不同热量层的多样化生物模型的影响.
确定与金属合CQDs相关的环境风险.

主要方法:

通过微波辅助技术合成金属合的CQD (Mn,Fe,Cu,Ag).
在细菌 (大肠杆菌,B. subtilis),植物 (Vigna radiata) 和哺乳动物细胞 (C2C12) 的体内生态毒性测试.
评估不同度和暴露时间的毒性.

主要成果:

用银添加的CQD (Ag-CQD) 显示出显著的毒性: ~85%的细菌死亡,100%的哺乳动物细胞死亡在10μg/mL,和~60%的根茎生长抑制在50μg/mL.
在经过测试的金属化CQD中,化CQD (Mn-CQD) 的毒性最低.
毒性根据金属剂的类型和生物模型大大不同.

结论:

在CQD中使用金属兴奋剂导致差异性生态毒性,而Ag-CQD带来了相当大的环境风险.
确定金属合CQD的安全度范围对于它们的可持续应用至关重要.
这些发现强调了对新型纳米材料的生态毒理学评估的重要性.

关键词:

碳量子点是指碳的量子点.环境可持续性环境可持续性金属兴奋剂的使用方法毒性评估毒性评估毒性评估热带水平热带水平热带水平

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