启动设置和与抗抑郁药物使用相关的因素在进入长期护理机构时
Georgina A Hughes1,2, Maria C Inacio2,3, Debra Rowett1,4
1University of South Australia, UniSA Clinical & Health Sciences, Adelaide, South Australia, Australia.
British journal of clinical pharmacology
|January 31, 2025
概括
进入长期护理机构 (LTCF) 的大多数老年人已经使用抗抑郁药. 在LTCF进入之前或期间开始服用抗抑郁药,取决于居民的特点和护理环境.
科学领域:
- 老年医学 老年医学
- 心理药理学 心理药理学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 抗抑郁药的使用在老年人中很常见,特别是那些过渡到长期护理设施 (LTCF) 的老年人.
- 了解抗抑郁药处方的发起地点对于优化这种脆弱人群的药物管理至关重要.
研究的目的:
- 对于进入LTCF的个人来说,对抗抑郁药开始的护理环境 (社区,医院或LTCF) 的特征.
- 为了确定与抗抑郁药启动设置相关的居民特征.
主要方法:
- 一项横截面研究分析了来自34,525名65-105岁的非土著居民进入澳大利亚LTCF (2015-2019) 的数据.
- 抗抑郁药的启动是通过在LTCF进入后两个月内选药品声明来确定的.
- 多变量逻辑回归确定了与启动设置相关的因素.
主要成果:
- 大多数居民 (78.7%) 在进入LTCF之前开始服用抗抑郁药;7.4%在医院开始服用,13.9%在LTCF开始服用.
- 米尔塔扎平是最常见的抗抑郁药,在医院和LTCF环境中开始使用.
- 老年居民 (≥90岁) 在LTCF中更有可能开始服用抗抑郁药,而最近的精神药物使用者在LTCF进入之前更有可能在社区环境中开始服用抗抑郁药.
结论:
- 在LTCF居民中,相当一部分抗抑郁药的使用在过渡前或过渡期间开始.
- 干预措施应考虑抗抑郁药开始的设置,时间和指示.
- 持续监测安全性和疗效对于优化LTCF的抗抑郁药物治疗至关重要.
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