在重症患者中开发和验证肠道食不耐症预测模型:一项回顾性队列研究
Lijie Liu1,2, Jin Li3, Liting Hu2
1School of Nursing, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Journal of clinical nursing
|January 31, 2025
概括
一种新的预测模型可以在营养的第一个星期内识别危急病患者,这些患者有风险患肠道食不耐受症. 这种工具有助于临床医生提供个性化的护理,并通过早期预测不耐受性来改善患者的结果.
科学领域:
- 关键护理医学 关键护理医学
- 临床营养学 临床营养学
- 预测建模的预测建模.
背景情况:
- 肠道食不耐症在重症患者中很常见.
- 早期识别有风险的患者对于优化营养和患者结果至关重要.
- 预测模型可以帮助临床医生管理肠道营养.
研究的目的:
- 开发和验证肠道食不耐受症的预测模型.
- 在重症患者中确定早期肠道食不耐受症的关键风险因素.
- 提供个性化风险评估和管理的工具.
主要方法:
- 这是一项回顾性队列研究,涉及471名重症患者.
- 使用单变量和逻辑回归分析开发预测模型.
- 使用歧视,校准和决策曲线分析评估模型性能.
主要成果:
- 肠道食不耐症的发生率为35.7%.
- 一个六个变量模型 (神经疾病,慢性胃肠道疾病,APACHE II评分,镇静剂,抑制酸性药物,血清白蛋白) 证明了强大的预测性能.
- 该模型显示出良好的区分,校准和临床实用性.
结论:
- 开发的预测模型准确地识别了患有早期肠道食不耐受风险的重症患者.
- 该模型在临床环境中具有实践应用的巨大潜力.
- 这种工具可以支持个性化护理策略,以减轻食不耐受.
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