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Updated: May 30, 2025

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以埃巴斯为媒介的E3结合酶MKRN1的不稳定性可以防止与代谢功能障碍相关的脂肪肝炎

Seungyeon Kim1, Hyun-Ji Han1, Hyunjin Rho1

  • 1Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.

Cellular and molecular life sciences : CMLS
|January 31, 2025
PubMed
概括

抗组胺剂埃巴斯在治疗代谢功能障碍相关的脂肪肝炎 (MASH) 方面表现有前途. 它抑制MKRN1,激活AMPK并减少肝损伤,为MASH提供了潜在的新疗法.

关键词:
由AMP激活的蛋白激酶 (AMPK)埃巴斯丁 (Ebastine) 是一种类型的药物.一个MKRN1一个MKRN1代谢功能障碍相关的脂肪肝炎 (MASH)

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