在独立的老年人中治疗糖尿病的萨尔科佩尼亚,有或没有甲福林:一个病例控制研究
Maísa Braga Aguiar1, Solomon Kim1, Adriana Bruscato Bortoluzzo2
1Discipline of Geriatrics and Gerontology, Paulista School of Medicine, Federal University of São Paulo, Rua dos Otonis, 863, Vila Clementino, São Paulo, SP, ZIP CODE 04025-002, Brazil.
Acta diabetologica
|January 31, 2025
概括
与非糖尿病人相比,患有控制良好的糖尿病 (DM) 的老年人没有增加肉症的风险. 在糖尿病患者中使用甲胺 (MTF) 也没有显示与肉症患病率的相关性.
科学领域:
- 老年学是一门学科.
- 内分泌学 在内分泌学.
- 肌肉生理学 肌肉生理学
背景情况:
- 麻症是一种常见的与年龄有关的疾病,不成比例地影响患有糖尿病的老年人.
- 主要降糖剂甲胺 (MTF) 正在研究其在与年龄有关的疾病中的潜在作用,但其对肌肉质量的影响仍然令人担忧.
研究的目的:
- 为了比较老年糖尿病患者在美特福明 (MTF) 治疗中与非MTF和非糖尿病 (NDM) 患者的肉症患病率.
- 调查MTF使用与老年人肉类的发展之间的关联.
主要方法:
- 分析了194名80岁以上的独立老年人.
- 使用手握强度 (HG),小腿周长 (CC) 和步行速度 (GS) 评估萨科佩尼亚.
- 使用了非参数统计分析和卡普兰-梅尔生存曲线.
主要成果:
- 在糖尿病和非糖尿病组之间没有观察到临床特征,功能,体重,体检或死亡率的显著差异.
- 在非糖尿病患者 (16.55%) 和糖尿病患者 (14.63%) 组中,肉症的患病率相似,严重病例没有统计差异.
- 在与使用MTF和不使用MTF的糖尿病患者进行比较时,没有发现与sarcopenia相关的变量之间的差异.
结论:
- 长寿人群中得到良好控制的糖尿病与非糖尿病人群相比,与增加的肉症或死亡风险无关.
- 在老年糖尿病患者中使用甲福明并没有显示与皮症发展有显著的关联.
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