从2019年到2023年,在卢州地区的八家医院中使用抗凝剂
Wei Luo1,2, Yan Li3, Jiali Yang1,2
1Department of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
PloS one
|January 31, 2025
概括
里瓦罗克萨班和低分子量肝素 (LMWH) 的使用量从2019-2023年增加,支出减少. 华法林和肝素的使用保持稳定,这表明利瓦罗克萨班和LMWH的未来应用有希望.
科学领域:
- 药物经济学 药物经济学
- 医疗保健服务研究 医疗服务研究
- 临床药房 临床药房
背景情况:
- 抗凝剂的选择是随着药物使用量的增加而面临的重大挑战.
- 评估区域抗凝剂趋势为优化医疗机构选择提供了洞察力.
研究的目的:
- 分析抗凝剂使用和支出的趋势.
- 为了告知最佳的抗凝剂选择策略.
主要方法:
- 在三级医院对抗凝血剂数据 (2019-2023) 的回顾性分析.
- 确定每日剂量 (DDDs) 和确定每日成本 (DDC) 的计算.
- 线性回归分析以检查利用率和支出趋势.
主要成果:
- 利瓦罗克萨班的利用率 (DDDs) 每年显著增加 (p <0.05),而低分子量肝素 (LMWH) 的使用率则逐渐增加.
- 集中采购在特定年份减少了里瓦洛克萨班和LMWH的消费.
- 里瓦洛克萨班的DDC显著下降 (p = 0.020),而肝素的DDC略有增加 (p = 0.042).
结论:
- 里瓦罗克萨班和LMWH的利用量增加,但它们的支出从2019-2023年减少.
- 华法林和肝素的利用率和支出保持稳定.
- 里瓦罗克萨班和LMWH显示出有前景的应用前景.
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