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相关概念视频

Introduction to Sensory Receptors01:31

Introduction to Sensory Receptors

3.0K
Sensory receptors are vital in our ability to perceive and interpret the world. Sensory receptors are specialized cells in the peripheral nervous system that respond to various stimuli and enable one to experience different sensations. Based on specific criteria, sensory receptors are classified into distinct types.
The first classification criterion is based on cell type, position, and function. Some receptor cells are neurons with free nerve endings, where their dendrites are embedded in the...
3.0K
Somatosensation01:33

Somatosensation

36.4K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.4K
Sensory Perception: Organization of the Somatosensory System01:11

Sensory Perception: Organization of the Somatosensory System

2.8K
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
2.8K
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

4.1K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
4.1K
Sensory Functions of the Skin01:16

Sensory Functions of the Skin

4.4K
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
4.4K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

871
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
871

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  1. 首页
  2. 自身受体在感觉中的作用.
  1. 首页
  2. 自身受体在感觉中的作用.

相关实验视频

Muscle Receptor Organs in the Crayfish Abdomen: A Student Laboratory Exercise in Proprioception
10:50

Muscle Receptor Organs in the Crayfish Abdomen: A Student Laboratory Exercise in Proprioception

Published on: November 18, 2010

22.3K

自身受体在感觉中的作用.

Cheng-Han Lee1, Jiann-Her Lin2,3,4, Shing-Hong Lin1

  • 1Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.

Science advances
|January 31, 2025

在PubMed 上查看摘要

概括
此摘要是机器生成的。

参与体位感应的自身受体在检测酸性疾病 (sngception) 中起着关键作用. 删除自身感受器中的酸感应离子通道3 (ASIC3) 可以防止酸引起的疼痛,这表明它们参与了这种感觉通路.

更多相关视频

Proprioception and Tension Receptors in Crab Limbs: Student Laboratory Exercises
12:58

Proprioception and Tension Receptors in Crab Limbs: Student Laboratory Exercises

Published on: October 24, 2013

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A Simple Non-invasive Method for Temporary Knockdown of Upper Limb Proprioception
07:42

A Simple Non-invasive Method for Temporary Knockdown of Upper Limb Proprioception

Published on: March 3, 2018

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相关实验视频

Muscle Receptor Organs in the Crayfish Abdomen: A Student Laboratory Exercise in Proprioception
10:50

Muscle Receptor Organs in the Crayfish Abdomen: A Student Laboratory Exercise in Proprioception

Published on: November 18, 2010

22.3K
Proprioception and Tension Receptors in Crab Limbs: Student Laboratory Exercises
12:58

Proprioception and Tension Receptors in Crab Limbs: Student Laboratory Exercises

Published on: October 24, 2013

25.1K
A Simple Non-invasive Method for Temporary Knockdown of Upper Limb Proprioception
07:42

A Simple Non-invasive Method for Temporary Knockdown of Upper Limb Proprioception

Published on: March 3, 2018

9.4K

科学领域:

  • 神经科学是一个神经科学.
  • 感官生理学 感官生理学
  • 疼痛研究 疼痛研究

背景情况:

  • 自身受体是机械感知神经元,对于监测肌肉状态和身体位置至关重要.
  • 虽然通常不是nociceptive,proprioceptors表达了亲nociceptive酸感应离子通道3 (ASIC3).
  • 自身受体在酸性感应 (sngception) 中的作用仍然在很大程度上未被探索.

研究的目的:

  • 研究自身受体在感知酸性疾病中的功能.
  • 为了确定自身受体中的ASIC3是否有助于酸引起的疼痛.

主要方法:

  • 基因删除ASIC3在自身受体与小鼠的恶性受体.
  • 自身受体的化学光遗传激活.
  • 在人体和脊髓损伤患者的肌肉内酸化.

主要成果:

  • 基因删除ASIC3,特别是在自身受体中,在小鼠中消除了酸性诱导的慢性过敏症.
  • 亲受体激活促进了高性原始化,有利于酸性诱导的慢性疼痛.
  • 在人类中,酸化诱导了酸感知,而不是疼痛;然而,一个脊髓受伤的患者保留了自身感知和认知.

结论:

  • 通过ASIC3,自身受体在感知酸性化 (sngception) 中发挥着重要作用.
  • 这些发现表明,自受体的功能超出了机械感觉,延伸到化学感觉.
  • 来自小鼠模型和人体研究的证据支持自身感受器参与sngception,可能通过脊柱脊柱介导.