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同进化残留物的计算设计,以提高酸酸酶的稳定性和活性

Jiaen Song1, Jun Qiao2, Zhongyi Cheng1

  • 1Key Laboratory of Industrial Biotechnology (Ministry of Education), School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China.

Biochemical and biophysical research communications
|January 31, 2025
PubMed
概括

研究人员增强了关键的工业酶 - - 化酶 (NHase),以提高活性和稳定性,使用一种新的共同进化的残留物重新设计策略. 这种优化的NH酶促进了高效的化到胺生物转化.

关键词:
催化活动是催化活动.同进化的残留物.计算设计 计算设计亚烯酸酸盐酸酶是什么热稳定性 热稳定性

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