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Updated: May 5, 2026

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空间转录学揭示了胰腺癌的中心和侵入性前端之间的癌症和干细胞异质性

Tine Norman Alver1, Helga Bergholtz1, Maia Blomhoff Holm2

  • 1Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Norway.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
|January 31, 2025
PubMed
概括

胰腺管腺癌 (PDAC) 显示空间异质性. 与瘤中心相比,在侵袭前线的癌细胞和癌症相关纤维细胞表现出增加的压力,增殖和上皮层-介质细胞过渡 (EMT) 途径活性.

关键词:
与癌症相关的纤维细胞.胰腺癌是一种癌症.空间转录学 空间转录学瘤生物学 瘤生物学

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