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桃切除术对口腔大癌发展的影响
Shirrell Glitzky1,2, Achim Franzen1,2, Annekatrin Coordes3,2
1Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Ruppin Brandenburg (UKRB), Brandenburg Medical School, Neuruppin, Germany.
Anticancer research
|January 31, 2025
概括
桃体切除术 (TE) 的病史与口腔支状细胞癌 (OPSCC) 相关,这种癌症从桃体转移到舌头底部. 然而,TE不会影响OPSCC患者的整体存活率或瘤特征.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 在西方社会,口腔状细胞癌 (OPSCC) 的发病率正在上升.
- 桃体切除术 (TE) 的发生率正在下降.
- TE历史与OPSCC发展之间的关系需要进一步调查.
研究的目的:
- 为了调查桃体切除病史与口腔大支状细胞癌的发展之间的联系.
- 分析OPSCC患者的瘤定位模式,有或没有TE病史的患者.
主要方法:
- 在2004年至2023年期间接受治疗的320名OPSCC患者的回顾性队列研究.
- 从德国一所大学医疗中心的数字患者病历中收集的数据.
- 在有 TE 病史和没有 TE 病史的患者之间比较瘤位置和生存结果.
主要成果:
- 19名患有OPSCC的患者 (5.9%) 有TE病史.
- 患有TE病史的患者在瘤位置上显示出显著差异 (p=0.010).
- 在有TE病史的患者中,OPSCC在桃体区域的频率较低 (16%对45%),在舌头底部的频率较高 (63%对29%).
结论:
- 桃体切除术的病史与桃体OPSCC的风险降低有关,特别是在成年时进行时.
- 在有TE病史的OPSCC患者中,瘤更常见地位于舌头底部.
- 桃体切除术史没有影响患者的人口统计学,瘤参数或整体预后.
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