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术后血清转胺酶的峰值与肝切除术后的肝衰竭和腹腔镜切除肝脏后的输入封闭有关

Hajime Kamiya¹, Taisuke Imamura², Hisashi Ikoma¹

¹Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Anticancer research

|January 31, 2025

概括

在腹腔镜切除肝脏后,异常高峰的术后血清氨基酶 (PST) 是肝切除术后肝衰竭的重要危险因素. 此外,PST水平还与手术期间输入阻塞的持续时间相关.

科学领域:

肝胆道手术是肝胆道的手术.
最少的侵入性手术是最少的侵入性手术.
手术瘤学手术瘤学

背景情况:

术后血清氨基酶 (PST) 峰值可能表明肝脏受切除和缺血-再输血损伤的损伤.
讨论了PST对结果的预测价值及其与入流阻塞持续时间的相关性.
对于腹腔镜切除肝脏 (LLR) 后的PST存在有限的数据.

研究的目的:

评估PST在预测LLR后结果方面的有效性.
调查PST与LLR输入阻塞持续时间之间的关系.

主要方法:

从2012年到2023年接受LLR的313名患者的回顾性分析.
评估PST-AST和PST-ALT用于预测肝切除术后肝衰竭 (PHLF).
在PST水平和入流阻塞持续时间之间的相关性分析.

主要成果:

在预测PHLF时,PST-AST和PST-ALT的准确性很高 (AUC为0.801和0.790).
异常高的PST (≥1,000 U/l) 是PHLF的独立风险因素 (OR=25.50).
PST水平与输入阻塞持续时间有显著的相关性 (Spearman 的 ρ=0.5306 对于 AST,0.5632 对于 ALT).

结论:

异常高的PST (≥1,000 U/l) 独立预测LLR后的PHLF.
在LLR之后的PST水平与入流阻塞的持续时间有关.

关键词:

转氨基酶是一种转氨基酶.输入阻塞的持续时间.腹腔镜肝脏切除术腹腔镜肝脏切除术肝切除术后的肝功能衰竭术后住院时间术后住院时间

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