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Updated: May 29, 2025

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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通过TRIM21介导的PRMT1降解减轻了结直肠癌恶性进展的速度

Menghan Cao1,2,3, Zhiying Shao2,4, Xingyou Qian2

  • 1Nanjing Medical University, Nanjing, Jiangsu, China.

Cell death & disease
|January 31, 2025
PubMed
概括

含有21 (TRIM21) 的三方基因在结直肠癌 (CRC) 中减少,与预后不佳相关. 通过降解PRMT1,TRIM21抑制了CRC的进展,这表明其作为预测生物标志物的潜力.

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