牙周病是否与妊娠期糖尿病有关? 探索证据证据的探索
Lata Goyal1, Mehak Gupta2, Shipra Gupta3
1Periodontology Division, Department of Dentistry, All India Institute of Medical Sciences, Bathinda, India. latagoyal83@gmail.com.
Evidence-based dentistry
|January 31, 2025
概括
牙周病与妊娠期糖尿病有关,增加了其发展的风险. 需要进一步的研究来确定这一关联.
科学领域:
- 产科和妇科 产科和妇科
- 牙周病学 牙周病学
- 公共卫生 公共卫生
背景情况:
- 孕期糖尿病 (GDM) 是怀孕期间的一个重大问题.
- 牙周病 (PD) 是一种常见的口腔感染.
- 需要进一步调查PD和GDM之间的潜在联系.
研究的目的:
- 系统地审查和元分析观察性研究,检查牙周病和妊娠糖尿病之间的关联.
- 在PD的存在下量化GDM的风险.
主要方法:
- 在多个数据库 (PubMed,Cochrane,Embase,虚拟健康图书馆) 进行了全面的文献搜索,截至2024年4月.
- 在元分析中包括了11项观察性研究,数据使用统计模型 (固定和随机效应) 提取和合成.
- 研究质量和出版偏差使用纽卡斯尔-太华标准,埃格尔测试和漏斗图进行了评估.
主要成果:
- 分析了11项涉及2032名患者的研究 (572名患有GDM).
- 在牙周病和妊娠期糖尿病之间发现了统计学上显著的关联.
- 分析显示,几率比 (OR) 为1.83 (95% CI:1.25-2.69,p < 0.0017),表明患PD的GDM风险增加.
结论:
- 牙周病与妊娠期糖尿病有关.
- 这些发现表明,PD可能会增加患GDM的风险.
- 需要更强有力的证据来最终确定这种关系.
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