三糖糖体质指数和喘之间的关联:来自NHANES 2011-2018年的证据
Sijia Yu1, Shiping Wu2, Shouxin Wei3
1Department of General Practice, Suining Central Hospital, Suining, China. YSJ230028@163.com.
这项研究发现,较高的甘油三-葡萄糖体重指数 (TyG-BMI) 与美国成年人喘患病率的增加有关. TyG-BMI可能作为监测喘的指标,需要进一步研究.
科学领域:
- 代谢健康和呼吸道疾病.
- 在慢性疾病中发现生物标志物
背景情况:
- 喘是一种普遍的慢性呼吸道疾病,发病率越来越高.
- 胰岛素抵抗 (IR) 与喘的发展有关.
- 三甘油-葡萄糖体重指数 (TyG-BMI) 是一种新的IR生物标志物,对其与喘相关性的研究有限.
研究的目的:
- 为了研究TyG-BMI与美国成年人的喘之间的关系.
- 评估TyG-BMI作为喘患病率的潜在指标.
主要方法:
- 使用国家健康和营养检查调查 (NHANES) 数据 (2011-2018) 的横截面研究.
- 从甘油三,禁食血糖和BMI计算了TyG-BMI.
- 使用了加权的多变量逻辑回归模型和子组分析.
主要成果:
- 在TyG-BMI和喘之间观察到积极的关联.
- 较高的TyG-BMI四分位数与喘患病率的增加相关 (OR: 1.561).
- 在基于性别,冠状动脉疾病和中风的子组中,观察到喘和TyG-BMI之间的显著相互作用.
结论:
- 在美国成年人中,TyG-BMI与喘有关.
- TyG-BMI显示出作为监测喘患病率的指标的潜力.
- 需要进一步的纵向研究来确认因果关系,并评估其在治疗并发症中的作用.
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