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睡眠行为和角质:一个广泛的审查

Alejandro Tello, Paula Alejandra Navarro, Angelica Pedraza-Concha

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti

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概括

睡眠姿势可能会影响形 (KC) 的发展. 倾斜或侧卧睡眠可能会增加角膜压力,但需要更多的研究来证实这种与角膜 (KC) 的联系.

科学领域:

眼科医生眼科眼科
角膜疾病角膜疾病
生物机械工程生物机械工程

背景情况:

角膜 (KC) 是一种影响角膜形状的渐进性眼睛疾病.
睡眠姿势的夜间眼睛压缩是KC的一个潜在的,研究不足的因素.
在睡眠期间,KC的不对称性可能会受到外部生物力学力量的影响.

研究的目的:

审查有关睡眠姿势与角质 (KC) 之间的关联的现有文献.
为了确定睡眠姿势的夜间眼睛压缩是否有助于KC发展或不对称.
综合关于睡眠位置对角膜健康的生物力学影响的证据.

主要方法:

对多个数据库 (CENTRAL,MEDLINE,EMBASE,LILACS,ClinicalTrials.gov) 和灰色文献进行了系统的范围审查.
纳入标准集中在检查睡眠姿势 (俯卧,横卧,仰卧) 和KC的研究上.
分析了10项涉及2322名参与者的研究,根据分析和非分析设计进行分类.

主要成果:

50%的研究 (非分析) 表明KC参数与夜间眼睛压缩之间存在相关性.
60%的分析研究 (五分之三) 报告说,睡眠姿势与KC风险之间存在统计学上显著的关联.
有证据表明,倾斜/侧卧睡眠与KC发育/不对称性之间存在潜在联系.

结论:

倾斜和侧卧的睡眠姿势可能会导致角 (KC) 发育或不对称.
这些姿势可能会在睡眠期间增加角膜生物力学压力.
进一步的研究对于验证发现和阐明因果机制至关重要.

关键词:

视角膜视角膜是一个不对称的角质.形 (keratoconus) 是一种形.睡眠睡眠睡眠睡眠睡眠睡眠行为睡眠行为

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