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Updated: Jul 1, 2026

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在小鼠皮肤上设计和评估循环实验.

Junyan Duan1, Satya Swaroop Karri2, Kiarash Forouzesh2

  • 1Center for Complex Biological Systems, University of California, Irvine, Irvine, California, USA; The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, California, USA.

The Journal of investigative dermatology
|February 1, 2025
PubMed
概括

鼠标的皮肤内有一个昼夜钟,它调节了代谢和免疫力等关键功能. 这项研究指导研究人员进行实验设计,研究皮肤昼夜节律及其在健康和疾病中的作用.

关键词:
生物信息学是一种生物信息学.循环节律是指循环节律.皮肤 皮肤 皮肤 皮肤转基因小鼠模型的模型.

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...