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在患有晚期甲状腺癌的患者中,TP53的变化与对伦瓦替尼的反应不佳有关

Valentina Cirello1,2, Carla Colombo1,2, Delfina Tosi3

  • 1Endocrine Oncology Unit, Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy.

The Journal of clinical endocrinology and metabolism
|February 1, 2025
PubMed
概括

在晚期甲状腺癌中,TP53突变预示着对lenvatinib的反应不佳. 患有TP53变化的患者经历了较短的无进展和整体存活时间,突出了治疗选择的潜在生物标志物.

关键词:
这就是TP53的特点.晚期甲状腺癌是什么?伦瓦提尼布 (Lenvatinib) 是一种药物.多酶抑制剂的使用差异化的甲状腺癌是差异化的甲状腺癌.对MKI的抗性.

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