在加达酸增强的MRI上结肠直肠肝转移:化疗后的典型特征下降
Denise J van der Reijd1, Ezgi A Soykan2, Birthe C Heeres3
1Department of Radiology, Antoni van Leeuwenhoek - The Netherlands Cancer Institute, Amsterdam, the Netherlands; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands.
Clinical imaging
|February 1, 2025
概括
用加多酸增强的MRI显示了结直肠肝转移 (CRLM) 中典型的成像特征. 化疗可以减少这些特征的发生率,特别是T2W超强度和扩散限制.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 结直肠肝转移 (CRLM) 在晚期结直肠癌中很常见.
- 准确的成像对于诊断和治疗监测至关重要.
- 用加多克西酸增强的MRI提供了详细的肝脏成像.
研究的目的:
- 为了评估CRLM典型成像特征的频率,用 gadoxetic 酸增强的MRI.
- 为了评估这些特征在化疗后如何变化.
主要方法:
- 对258名患有CRLM的患者进行了回顾性分析,这些患者接受了加达酸增强的MRI.
- 基于6个定义的典型成像特征,对722个CRLM进行评估.
- 化疗前和化疗后CRLM中的成像特征的比较.
主要成果:
- 49%的化学疗法以前的CRLM显示所有六个典型特征;这下降到化学疗法后的25%.
- 低血管性 (98%) 和肝胆阶段没有增强 (100%) 非常普遍.
- 化疗后,T2W轻度高强度 (95%至79%) 和扩散限制 (87%至65%) 显著下降.
结论:
- CRLM表现出多种典型的成像特征,这些特征在加达酸增强的MRI上是典型的.
- 动脉边缘增强是最不常见的特征.
- 化疗改变了典型的MRI特征,特别是减少T2W超强度和扩散限制.
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