胃癌健康状况的实用值:一个系统的审查
Cristian Gonzalez1, Manuel Espinoza2, Matías Libuy1
1Escuela de Salud Pública, Universidad de Chile, Santiago de Chile, RM, Chile.
Value in health regional issues
|February 1, 2025
概括
本综述综合了胃癌 (GC) 阶段的实用值. 随着GC的晚期,实用值会下降,这凸显了患者偏好在医疗保健决策中的重要性.
科学领域:
- 卫生经济学 卫生经济学
- 在瘤学瘤学.
- 生活质量研究 研究 生命质量研究
背景情况:
- 胃癌 (GC) 对全球健康造成重大负担,可用的治疗方法往往会产生高成本并影响患者的生活质量.
- 实用值反映了患者对健康状况的偏好,对于健康和经济决策至关重要.
- 目前对不同GC阶段的实用值的系统化信息有限.
研究的目的:
- 系统地审查和分析现有的关于与胃癌各个阶段相关的实用值的文献.
- 为提供GC实用值的最新概述,并分析疾病阶段的相关性.
- 通过纳入患者偏好,为医疗保健政策和临床决策提供信息.
主要方法:
- 在PubMed,Embase,MEDLINE和Cochrane图书馆进行了全面的文献搜索.
- 报告从直接和间接方法获得的效用值的研究被选中进行分析.
- 提取的数据经过评估,随后随机效应元分析按GC健康状况分层.
主要成果:
- 包含4585名患者的12项研究被纳入了元分析.
- 平均效用值随GC阶段逐渐下降:第一阶段 (0.77),第二阶段 (0.75),第三阶段 (0.70) 和第四阶段 (0.64).
- 在所有实用价值估计中观察到显著的异质性.
结论:
- 本系统性审查提供了对胃癌的实用值的综合理解,强调了特定阶段的差异.
- 用实用值表示的患者偏好是制定政策和在GC管理中的临床实践中至关重要的考虑因素.
- 这些发现强调需要将患者报告的结果纳入医疗保健经济评估.
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