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Updated: May 29, 2025

Generation of Human Brain Organoids for Mitochondrial Disease Modeling
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线粒体疾病的iPSC模型

Sonja Heiduschka1, Alessandro Prigione2

  • 1Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Germany.

Neurobiology of disease
|February 1, 2025
PubMed
概括

人类诱导的多能干细胞 (iPSC) 为研究影响多个器官的复杂线粒体疾病提供了新的途径. 这项研究回顾了iPSC模型如何推动这些具有挑战性的疾病的治疗发现.

关键词:
大脑有机体是大脑中的有机体.疾病建模 疾病建模药物发现 药物发现线粒体疾病是线粒体疾病.多能干细胞是多能干细胞.

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