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Cytotoxic T Cells-mediated Immune Response

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...

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Updated: Jun 24, 2026

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Published on: June 23, 2014

对抗核抗体测试的历史视角

Gyorgy Abel¹, M Qasim Ansari², Melissa R Snyder³

¹G. Abel, MD, Laboratory Medicine and Pathology, Lahey Hospital and Medical Center, Beth Israel Lahey Health, Burlington, Massachusetts.

The Journal of rheumatology

|February 1, 2025

概括

了解抗核抗体 (ANA) 测试的历史和演变对于准确诊断自身免疫性疾病至关重要. 本综述详细介绍了各种ANA测试方法,它们的优缺点以及改善患者护理的当前做法.

科学领域:

免疫学免疫学免疫学
临床化学临床化学

背景情况:

抗核抗体 (ANA) 在20世纪50年代末被发现,自20世纪80年代以来,标准化测试一直在发展.
经典的间接免疫光测定 (IFA) 和较新的免疫化学技术用于ANA检测.

关键词:

抗核抗体是一种抗核抗体.这是自抗体的自抗体.这是自身免疫力.生物标志物生物标志物系统性自身免疫性类风湿性疾病系统性红血性狼 (Systemic Lupus Erythematosus) 是一种全身性狼.

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Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay

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