美国成年人的心脏代谢指数和高血压之间的关联来自NHANES 1999-2020年
Tuo Guo1,2, Yang Zhou3,4, Guifang Yang1,2
1Department of Emergency Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Scientific reports
|February 1, 2025
概括
心脏代谢指数 (CMI) 比BMI更好地评估心血管风险. 较高的CMI与高血压患病率的增加有关,特别是在女性中,突出了其在风险评估中的价值.
科学领域:
- 心血管健康 心血管健康
- 代谢综合征是代谢综合征的一种.
- 公共卫生 公共卫生
背景情况:
- 高血压是全球主要的死亡原因.
- 像BMI这样的传统指标不充分评估与肥胖有关的心血管风险.
- 心脏代谢指数 (CMI) 提供了对内脏脂肪和代谢功能障碍的优越评估.
研究的目的:
- 调查心脏代谢指数 (CMI) 与高血压患病率之间的关联.
- 探索非线性关系并确定CMI对高血压的值影响.
- 评估不同美国人群的研究结果的一致性.
主要方法:
- 分析了来自国家健康和营养检查调查 (1999-2020) 的45250名参与者.
- 多变量逻辑回归来检查CMI和高血压的关联.
- 限制立方线和两部分线性回归用于非线性分析和值识别.
主要成果:
- 高血压患者的CMI水平显著更高 (中位数为0.73比0.46).
- 增加的CMI显著与更高的高血压患病率相关 (OR 1.30,95% CI 1.25-1.35).
- 观察到非线性L形关联,临界CMI值为1.37;女性表现出更明显的效应.
结论:
- 心脏代谢指数 (CMI) 显示与高血压有显著的关联.
- 与传统指标相比,CMI提供了一个更准确的心血管风险评估工具.
- 这些发现支持CMI在识别不同美国人群中,特别是女性中,有风险的个人的实用性.
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