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高分辨率红外成像性能新高数值光圈的施瓦茨希尔德目标

Karolina Kadela¹, Honorata Oleś², Karolina Kosowska²

¹Solaris National Synchrotron Radiation Centre, Jagiellonian University, 98 Czerwone Maki Str. 30-392 Krakow, Poland; Łukasiewicz Research Network - Krakow Institute of Technology, 73 Zakopiańska Str. 30-418 Krakow, Poland; Doctoral School of Exact and Natural Sciences, 11 Łojasiewicza Str. 30-348 Krakow, Poland.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

|February 2, 2025

概括

新的高数值孔径 (NA) 红外反射目标显著提高了在化学成像中红外 (IR) 显微镜中低于3μm的空间分辨率和信号噪声比 (SNR).

科学领域:

光学和光谱学,以及光学和光谱学.
材料科学材料科学材料科学
生物医学成像技术生物医学成像技术

背景情况:

中红外 (IR) 显微镜可提供微米级的化学成像,但其衍射受限.
折射镜头遭受着色谱偏差,限制了宽带的使用.
新的高数值光圈 (NA) 反射目标旨在克服这些局限性.

研究的目的:

描述新的高NAIR反射镜的空间分辨率和信号噪声比 (SNR).
将他们的业绩与已确定的IR目标进行比较.
为了评估它们与传统的IR源的有效性.

主要方法:

0.7 NA (20x) 和0.78 NA (40x) IR反射目标的表征.
与0.4 NA (15x) 和0.52 NA (36x) 目标的性能比较.
在聚合物和组织样本上使用台式红外显微镜进行测试.

主要成果:

空间分辨率低于3μm,可以在最短的波长上实现最高的NA目标.
大约6μm的分辨率与最低的NA目标获得.
高NA目标在传输和转折几何学上都显示出优越的SNR.

结论:

新的高NAIR反射目标显著提高了微光谱中的空间分辨率和SNR.
这些目标使得使用传统的红外线源能够对聚合物和组织进行详细的化学成像.
改进的性能推动了在中红外范围的衍射有限成像的边界.

关键词:

生物医学红外光谱学里埃变换红外成像技术的红外成像技术高清高清是什么意思聚甲酸) 的球体.空间分辨率的空间分辨率组织成像成像技术

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