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Updated: May 13, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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通过一个结构灵感的虚拟查研究发现了新的微小细胞质前列腺素E2合成酶1 (mPGES-1) 抑制剂

Abdurrahman Olğaç1, Paul M Jordan2, Christian Kretzer2

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University, 06560, Ankara, Turkey; Department of Drug Discovery, Evias Pharmaceutical R&D Ltd., Gazi Teknopark, 06830, Ankara, Turkey.

Journal of molecular graphics & modelling
|February 2, 2025
PubMed
概括

研究人员选化合物,以发现新的微小性质前列腺素E2合成酶-1 (mPGES-1) 抑制剂. 最强效的化合物显示出显著的抑制,为更安全的抗炎药物提供了潜力.

关键词:
阿拉基酸 是一种循环氧化基因酶 (Cyclooxygenase) 是一种停靠的对接方式在前列腺腺内.虚拟选是一个虚拟的选.mPGES-1 的使用情况.

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