在黄色羽毛 brojlers的肠道中发现的阿斯塔克桑对健康的影响
Yu-Yun Gao1, Zhi-Xin Lin1, Min Zhang1
1College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Poultry science
|February 2, 2025
概括
通过增强肠道形态和屏障功能,阿斯丁 (AST) 补充剂改善了 brojlers 的肠道健康. 它还调节了粘膜免疫力,调节了肠道微生物群的多样性和结构.
科学领域:
- 动物科学动物科学
- 营养科学 营养科学
- 免疫学 免疫学 免疫学
背景情况:
- 阿斯塔丁 (AST) 是一种类胡卜素,具有已知的抗氧化,抗炎和调节亡的特性.
- 然而,它对肠道健康的具体影响,特别是对家禽的影响,在很大程度上仍未被阐明.
研究的目的:
- 为了研究食中阿斯塔桑对肠道形态,屏障功能,粘膜免疫和黄羽毛肉的头菌群的影响.
- 探索阿斯塔克桑影响肉肠道健康的潜在机制.
主要方法:
- 288只雄性黄羽肉被随机分配到四个饮食组:对照组 (基础饮食) 和三个阿斯塔丁补充剂水平 (20,40,80毫克/公斤).
- 分析了肠道形态,粘膜免疫标记物 (细胞因子),紧结蛋白表达,血清D-乳酸,以及肠道微生物群的多样性和结构.
主要成果:
- 阿斯塔丁补充剂显著增加了头的高度和与密室的比率,同时降低了密室深度.
- 它通过降低IL-1β和IL-6和增加IL-4表达来调节免疫反应,同时对ZO-1紧结蛋白表达进行上调,并减少血清D-乳酸.
- 阿斯塔丁改变了内微生物群的组成,影响了特定细菌群的多样性和相对丰度.
结论:
- 食阿斯塔克桑有效地改善了 brojlers 的肠道形态和屏障功能.
- 素调节肠道粘膜免疫力,并对肠道微生物群的多样性和结构产生积极影响.
- 这些发现凸显了阿斯塔克桑在维持和增强肉肠道健康方面的多方面的作用.
相关概念视频
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02:41Lethal Alleles
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Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...