在有阅读困难史的个体中,thalamocortical连接的微结构横向化
Yueye Zhao1, Jianyi Liu1, Xue'er Ma1
1School of Psychology, Shaanxi Normal University, Xi'an, 710062, Shaanxi, China.
NeuroImage
|February 2, 2025
概括
阅读困难的个体表现出lamus和皮质之间的白质连接发生变化. 额头 - thalamic通道的右向横向化与这些人早期阅读能力较差相关.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 神经成像是一种神经成像.
背景情况:
- 泰拉木斯在阅读中起着至关重要的作用,其功能与皮层连接有关.
- 这些甲状腺皮层连接与阅读能力相关的侧面化仍未得到充分探索.
研究的目的:
- 为了研究不同阅读能力的成年人中甲状腺皮层白质道中的微观结构差异和侧面化.
- 探索这些微观结构性质,阅读技能和早期阅读表现之间的关系.
主要方法:
- 利用扩散权重成像和受约束球形解卷 (CSD) 模型来重建皮层白质段.
- 应用神经元导向分散和密度成像 (NODDI) 模型来评估微结构性质 (NDI,ODI,VISO) 并计算侧面化指数.
- 包括26名阅读困难的成年人和35名典型的成年人,评估阅读准确性,语音意识和快速自动化命名.
主要成果:
- 阅读困难的成年人在正面 - thalamic和尾 - thalamic通道中表现出明显较低的神经元密度指数 (NDI),与善于阅读的人相比.
- 额头 - thalamic白质道的右侧化增加与阅读困难的个体早期阅读表现较差有关.
结论:
- 在有阅读困难史的成年人中存在非典型的thalamocortical白质连接.
- 这些连接的横向化程度受早期阅读困难的严重程度的影响.
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