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Updated: May 29, 2025

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
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阿利索尔A24-酸盐通过向美华酸盐生物合成来对抗抗甲素耐药黄金葡萄球菌感染

Li-Jie Liang1, Bing He1, Yin Liang2

  • 1Institute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences, Fuzhou 350013, China; Guangdong Laboratory for Lingnan Modern Agriculture, National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics, Development and Safety Evaluation, South China Agricultural University, Guangzhou 510642, China.

Biochemical pharmacology
|February 2, 2025
PubMed
概括

阿里索尔A24-酸盐 (AA) 通过抑制美酸盐合成,有效地对抗抗甲素耐药黄金葡萄球菌 (MRSA). 这种化合物恢复了对抗生素的敏感性,并减少了MRSA的毒性和炎症.

关键词:
艾利索尔A24-乙酸 (AA) 是一种宿主免疫反应 宿主免疫反应膜生理学 膜生理学甲素耐药黄金葡萄球菌 (MRSA) 是一种梅瓦诺酸盐 (MVA) 生物合成

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