骨质疏松症患者在风湿病学环境中的心血管风险. 来自西班牙基于调查的多中心研究的结果
Enrique Casado1, Irene Gómez-Olmedo2,
1Rheumatology Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, Sabadell, Barcelona, Spain.
Reumatologia clinica
|February 2, 2025
概括
骨质疏松症患者经常有心血管风险,影响治疗选择. 风湿病学家经常避免服用某些骨质疏松症药物,如罗莫苏祖马布,SERM和MHT,当心血管风险因素存在时.
科学领域:
- 内分泌学 在内分泌学.
- 心脏病学 心脏病学
- 类风湿病学 类风湿病学
背景情况:
- 骨质疏松症 (OP) 和心血管疾病 (CVD) 具有共同的病理生理机制和危险因素.
- OP的严重程度与心血管 (CV) 风险相关,需要综合的临床方法.
- 了解OP患者的并发症和心血管风险因素 (CVRF) 对治疗决策至关重要.
研究的目的:
- 评估西班牙风湿病学机构OP患者的并发症,特别是CVD和CVRF的频率.
- 评估CVRF对OP治疗选择的影响.
主要方法:
- 一项西班牙基于调查的多中心研究,涉及62名风湿病学家.
- 从每位风湿病学家的最后10名患者收集的数据,重点关注OP和CVRF概况以及处方习惯.
- 评估CVRF是否影响了OP治疗的选择.
主要成果:
- 来自620名患者的数据显示,主要是女性 (85.2%),主要是OP (73.2%).
- 常见的并发症包括炎症性风湿性/自身免疫性疾病,内分泌病变和主要心血管疾病.
- 在82.3%的风湿病学家中,CVRF影响了治疗选择,从而避免了罗莫苏祖马布,SERM和MHT.
结论:
- 大多数OP患者是初级OP的女性,经常出现CVRF.
- 口服双酸盐,代诺苏马布和特里巴拉提德是首选的OP治疗方法.
- 在OP患者中,MHT,SERM和romosozumab通常被避免使用.
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