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怀孕30-33周婴儿早期排外肠道养:一项随机对照试验

Belal N Alshaikh^1,2, Ossama Hassan³, Wissam Alburaki^4,5

¹Neonatal Gastroenterology and Nutrition Program, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. balshaik@ucalgary.ca.

Journal of perinatology : official journal of the California Perinatal Association

|February 2, 2025

概括

对早产婴儿的早期排他性肠道养 (EEEF) 是可行的和有效的. 这种方法显著减少了达到全肠道养的时间,并缩短了住院时间.

科学领域:

新生儿营养新生儿营养
儿科胃肠病学儿科胃肠病学
临床试验研究临床试验研究

背景情况:

过早出生的婴儿往往需要专门的养策略.
优化营养供应对于婴儿发育和健康结果至关重要.
临床试验.gov的标识符:NCT03708068.

研究的目的:

评估早期排他性肠道养 (EEEF) 的可行性和有效性.
确定EEEF是否可以缩短早产婴儿的全肠养时间.

主要方法:

一项实用随机对照试验,涉及30 0/7至33 6/7周怀孕期间出生的婴儿.
婴儿被随机分配,接受EEEF或常规的静脉注射液体养.
在两组中,料量都逐渐增加.

主要成果:

在EEEF组的婴儿更快地达到全肠养 (平均差异-1.2天).
EEEF显著降低了对腹腔营养和中央静脉通道的需求.
接受EEEF的婴儿住院时间较短 (平均差异 -6.6天).

结论:

早期纯肠养是早产婴儿的可行和有益的策略.
EEEF加速了全肠养的实现,并减少了整体住院时间.
这种养方法为中度早产婴儿提供了显著的临床优势.

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