相关实验视频

Updated: May 29, 2025

Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue
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Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue

Published on: November 30, 2018

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异体化基H4的半合成揭示了染色体对分子衰老的强度和脆弱性

Tianze Zhang1, Luis F Guerra1, Yana Berlina2

  • 1Department of Chemistry, King's College London, Britannia House, 7 Trinity Street, London SE1 1DB, U.K.

Journal of the American Chemical Society
|February 3, 2025
PubMed
概括

蛋白质老化可能导致酸 (Asp) 形成异酸 (isoAsp). 在位置24 (H4isoD24) 的Histon H4进行了研究. H4isoD24会影响组织蛋白甲基化,但不会影响染色体的紧缩或重塑.

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In Vitro Characterization of Histone Chaperones using Analytical, Pull-Down and Chaperoning Assays

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Reconstitution of Nucleosomes with Differentially Isotope-labeled Sister Histones09:26

Reconstitution of Nucleosomes with Differentially Isotope-labeled Sister Histones

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Histone Modification02:32

Histone Modification

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Spreading of Chromatin Modifications

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The writer...
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Chromatin Modification in iPS Cells

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