门诊临床医院抗生素处方的决定因素:区域观察性研究
Patrick D Crowley1, Francis X Whalen2, Leslie R Siegel3,4
1Division of Public Health, Infectious Disease, and Occupational Medicine, Mayo Clinic, Rochester, MN, USA.
近20%的临终关怀患者接受抗生素治疗,肺部疾病患者或更长的存活率更高. 澄清患者在临终关怀中使用抗菌素的偏好至关重要.
科学领域:
- 医学研究 医学研究
- 抚慰性护理是一种缓解性护理.
- 药理学 药理学是指药理学的学科.
背景情况:
- 临终关怀患者接受了关于抗生素偏好的调查.
- 关于影响住院抗生素使用的因素的数据有限.
- 这项研究描述了在门诊临终关怀机构处方抗生素的情况.
研究的目的:
- 为了确定与宿舍抗生素使用相关的患者特征.
- 为了为有关宿舍患者抗生素偏好的讨论提供信息.
- 提供有关门诊临床医院的抗生素处方模式的数据.
主要方法:
- 在门诊住院治疗的6452名患者 (2017-2023) 的回顾性审查.
- 基于临终关怀资格条件 (HQC),年龄,性别,生存时间和查尔森并发症指数的抗生素处方分析.
- 调整的赔率比率 (aOR) 的计算,以确定重要的因素.
主要成果:
- 19.5%的患者接受了抗生素;头类是最常见的.
- 患有肺HQC的患者更有可能接受抗生素 (aOR1.85).
- 较长的存活时间与较高的抗生素使用相关 (47.7%>6个月vs4.6%<7天).
结论:
- 在临终关怀中,抗生素处方很常见,特别是在肺部疾病和更长的存活期.
- 患者的年龄和性别没有显著影响抗生素接收.
- 在宿舍入院时,明确患者对抗微生物药物使用的偏好至关重要.
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