一个具有挑战性的病例,在没有经典的胰腺病理学发现的情况下,产生了酸性带炎
Cristo Armando Carrasco Mendoza1, Alexander Rolando Gomez-Lara1, Brian Matthew Kleker2
1Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA, USA.
The Permanente journal
|February 3, 2025
概括
乙酸性膜炎 (EF) 是一种罕见的皮肤疾病,模仿着硬化皮质. 诊断需要排除全身性硬化症 (SSc),并可能涉及成像和活检,尽管发现可能是不典型的.
科学领域:
- 皮肤病学 皮肤病学
- 类风湿病学 类风湿病学
- 病理学 病理学 病理学
背景情况:
- 乙酸性膜炎 (EF) 呈现的症状重叠局部性硬化症和全身性硬化症 (SSc).
- 由于这些重叠的临床特征,精确诊断EF具有挑战性.
- 区分EF与类似的条件需要全面的实验室,本病理学和成像评估.
研究的目的:
- 在75岁的女性中呈现一种异常呈现的乳清性带炎 (EF) 病例.
- 突出了区分EF与局部性硬化和全身性硬化 (SSc) 的诊断挑战.
- 为了说明高级成像和活检在诊断EF中的作用.
主要方法:
- 一个75岁的女性患者的临床表现审查.
- 局部性硬化症和全身性硬化症 (SSc) 的排他性诊断工作由风湿学.
- 磁共振成像 (MRI) 用于 Fascial 的评估.
- 整体带活检用于组织病理学检查.
主要成果:
- 患者表现出痛苦的,紫色的皮疹,胀,腹部紧张,体重减轻和呼吸不良.
- 风湿学工作成功排除了局部性硬化和全身性硬化 (SSc).
- 磁力共振扫描显示了形,支持了EF的怀疑.
- 带活检结果不是EF的经典,表明诊断复杂性.
结论:
- 乙性带炎 (EF) 诊断可能是复杂的,特别是非典型的表现.
- 排除全身性硬化症 (SSc) 和特征性MRI发现对于怀疑EF至关重要.
- 活检上的非典型组织病理学发现可能需要进一步调查或在EF诊断中进行临床相关性.
相关概念视频
Gastritis-I: Introduction and Types
3.8K
Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
3.8K
Gastritis-II: Pathophysiology
1.9K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.9K
Peptic Ulcer Disease I: Introduction
1.2K
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
1.2K
Peptic Ulcer
53
Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the...
53
Gastritis II: Pathophysiology
89
The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
89
Peptic Ulcer Disease I: Introduction
72
Peptic ulcer disease (PUD) involves breaks in the gastrointestinal tract's mucosal lining, primarily in the stomach and duodenum, with less frequent occurrences in the lower esophagus or near the pylorus.Ulcers can be acute or chronic. Acute ulcers are short-lived with minimal inflammation and heal quickly after the irritant is removed. Chronic ulcers persist, may recur, and often cause scarring due to ongoing tissue damage. Superficial erosions affect only the mucosal layer and are called...
72


