在儿童中,沙门氏菌非类型和西格拉菌相关的血性腹的负担和抗生素敏感性
Abir Rashid Al Sinani1, Tawfiq Taki Al Lawati1, Hajar Musabah Al Saadi1
1Department of Pediatrics, Rustaq Hospital, Rustaq, Oman.
Oman medical journal
|February 3, 2025
概括
非伤寒型沙门氏菌 (SNT) 和西格拉菌的腹在儿童中很常见. SNT对氏和安培敏感,而Shigella表现出耐药性,需要根据年龄和培养结果进行向抗生素治疗.
科学领域:
- 儿童传染病 儿童传染病
- 微生物学 微生物学
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 全球范围内,腹疾病仍然是儿童发病的重要原因.
- 非伤寒型沙门氏菌 (SNT) 和西格拉菌是常见的细菌病原体,导致儿童腹.
- 了解局部抗菌素敏感性模式对于有效治疗至关重要.
研究的目的:
- 为了确定SNT和Shigella腹在患有血性腹的儿童中的频率.
- 在这个儿科群体中评估SNT和Shigella分离物的抗生素敏感性概况.
- 为儿童细菌性腹提供经验性治疗指南.
主要方法:
- 从2019年6月到2023年6月,对患有血性腹的儿童进行了一项回顾性研究.
- 收集的数据包括人口统计,症状,血液测试和便细菌培养与抗菌素敏感性测试.
- 分析了便样本以检测沙门氏菌和西格拉菌的生长.
主要成果:
- 在1160名腹儿童中,有153名 (13.2%) 患有血性腹. 其中92人 (60.1%) 呈沙门氏菌或西格拉菌阳性测试结果.
- 在58名儿童 (63.0%) 中发现了SNT,在34名儿童 (37.0%) 中发现了Shigella. 一岁以下的三名儿童患上了细菌血症.
- 在SNT中,表现出对 ceftriaxone,ampicillin 和 ciprofloxacin 的高度敏感性. 石格拉对 ceftriaxone 和 ciprofloxacin 的耐药性很高,对 ceftriaxone 的敏感性仅为 46.9%.
结论:
- 非伤寒型沙门氏菌在5岁以下的儿童中更为普遍,而石氏菌在年龄较大的儿童中更为普遍.
- 沙门氏菌分离物对氏和安西林敏感,而西格拉菌对西普洛克萨有显著的耐药性.
- 建议在1岁以下的儿童接受经验性治疗,使用氏或安培;较大的儿童需要培养导向治疗,因为Shigella的抵抗模式.
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