在健康受试者中短期摄入delta-tocotrienol对脂质概况的影响
Naho Serizawa1,2, Yusuke Ninomiya3, Akiho Shinagawa4,5
1Department of Nutritional Sciences, Faculty of Health and Sports Sciences, Toyo University, Kita-ku, Tokyo 115-8650, Japan.
Journal of clinical biochemistry and nutrition
|February 3, 2025
概括
在健康的成年人中,短时间服用德尔塔托克醇 (δ-T3) 显著增加了血液中的δ-T3水平. 这项研究表明 δ-T3 .
科学领域:
- 营养科学 营养科学
- 生物化学 生物化学
- 人体生理学 人体生理学
背景情况:
- 德尔塔-托科特里昂醇 (δ-T3) 以其对脂质代谢的有益作用而闻名.
- 在日本人群中饮食摄入后血液中托克醇水平的定量变化存在有限的数据.
研究的目的:
- 为了研究短期补充三托克醇 (δ-T3) 对血δ-T3度的影响.
- 为了评估 δ-T3 和α-托科菲醇 (α-TP) 摄入对健康个体脂质谱的影响.
主要方法:
- 一项为期14天的交叉研究,涉及对照组,α-托科菲罗尔 (α-TP) 组 (264毫克/天) 和三角形托科特里诺尔 (δ-T3) 组 (250毫克/天).
- 在补充期间之前和之后测量了血 δ-T3 度和脂质谱 (包括HDL-C).
主要成果:
- 血δ-T3度从补充剂前的水平 (0.11 ± 0.03 μmol/L) 显著增加到补充剂后的水平 (0.40 ± 0.19 μmol/L) 在服用δ-T314天后.
- 无论是α-TP还是δ-T3补充剂都没有显著改变整体脂质特征.
- 观察到高密度脂蛋白胆固醇 (HDL-C) 的增加趋势与δ-T3摄入量 (前:59 ± 17至后:64 ± 20毫克/分升).
结论:
- 在健康的年轻成年人中,短期摄入三托克醇 (δ-T3) 有效地提高了血δ-T3水平.
- δ-T3补充剂显示出预防动脉样硬化的潜力,需要进一步调查.
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