在生物医学研究中实现端到端的安全联合学习,在异质计算环境中使用 APPFLx
Trung-Hieu Hoang1, Jordan Fuhrman2, Marcus Klarqvist3
1Department of Electrical and Computer Engineering and Coordinated Science Laboratory, University of Illinois at Urbana-Champaign, Urbana, 61801, IL, USA.
Computational and structural biotechnology journal
|February 3, 2025
概括
APPFLx是一个新的联合学习 (FL) 框架,可以在机构之间安全地训练机器学习模型,而无需共享敏感的健康数据. 这样可以加强协作和模型性能,同时保护患者的隐私.
科学领域:
- 生物医学机器学习
- 联邦学习学习 (Federated Learning) 是一种学习方式.
- 数据 隐私 数据 隐私 数据
背景情况:
- 大规模的生物医学机器学习 (ML) 项目需要跨机构的安全合作.
- 现有的联合学习 (FL) 环境在确保数据机密性方面面临挑战,特别是在受保护的健康信息方面.
- 跨机构研究受到行政和数据安全边界的阻碍.
研究的目的:
- 介绍APPFLx,一个低代码,用户友好的FL框架,旨在安全,跨机构的生物医学ML.
- 实现安全的端到端通信,保护隐私的功能和强大的身份管理.
- 促进FL在没有修改的情况下部署到现有的计算基础设施中.
主要方法:
- 开发了APPFLx,这是一个支持安全FL实验设置和执行的框架.
- 通过两项生物医学案例研究证明了APPFLx的实用性:ECG的年龄预测和X射线图的COVID-19检测.
- 利用异构的计算资源,包括本地和云设施,进行安全的模型培训.
主要成果:
- APPFLx成功促进了机器学习模型对敏感生物医学数据的安全,跨机构培训.
- 使用APPFLx进行训练的联合学习模型与集中式模型相比,显示出更好的概括性和性能.
- 在整个培训过程中,数据仍然受到保护,确保了患者的隐私.
结论:
- APPFLx是一个有效且易于使用的框架,可以加速跨组织的生物医学研究.
- 该框架增强了对大型数据集的合作,同时保持了对私人医疗数据的强有力的保护.
- APPFLx克服了行政障碍,使医疗保健机构的安全和高效的联合学习成为可能.
关键词:
生物医学研究的研究.发现COVID-19的检测方法胸部X射线成像 胸部X射线成像云计算是一种云计算.电心电图 (ECG) 是一种心电图.为了科学而联合学习.作为服务的功能.身份管理是指身份管理.保护隐私 - 保护隐私更多相关视频
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