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Updated: May 29, 2025

Surgical Injury to the Mouse Pancreas through Ligation of the Pancreatic Duct as a Model for Endocrine and Exocrine Reprogramming and Proliferation
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胰腺损伤诱导了axolotl中的β细胞再生

Connor J Powell1,2, Hani D Singer1, Ashley R Juarez1

  • 1Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity 10 Ave., Cambridge, MA, USA, 02138.

bioRxiv : the preprint server for biology
|February 3, 2025
PubMed
概括

在受伤后,阿克索洛特脏的再生涉及整个器官的β细胞增殖,而不是血清瘤的形成. 这一过程恢复了β细胞质量和胰腺功能,有助于从糖尿病相关损伤中恢复.

关键词:
补偿性增长是一种补偿性增长.糖尿病 糖尿病患者 糖尿病患者在这种情况下,胰岛素胰岛素.胰腺切除术是什么意思它们的扩散和扩散.切除 切除 切除 切除

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Tissue Renewal without Stem Cells01:23

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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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