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Updated: May 29, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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ADAR1 通过 MDM2 调节脂质重塑,以决定铁丧的敏感性

Che-Pei Kung, Nick D Terzich, Ma Xenia G Ilagen

    bioRxiv : the preprint server for biology
    |February 3, 2025
    PubMed
    概括

    作用于RNA 1 (ADAR1) 的腺氨酸脱氨酶可以保护侵袭性三阴性乳腺癌 (TNBC) 免受细胞死亡. 抑制ADAR1使TNBC对铁亡敏感,为这种具有挑战性的癌症提供了新的治疗脆弱性.

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